| Sid (voice) | 约翰·雷吉扎莫
 | |
| Manny (voice) | 雷·罗马诺
 | |
| Ellie (voice) | 奎恩·拉提法
 | |
| Diego (voice) | 丹尼斯·利瑞
 | |
| Scrat (voice) | 克里斯·韦奇
 | |
| Eddie (voice) | 乔希·佩克
 | |
| Shira (voice) | 詹妮弗·洛佩兹
 | |
| Crash (voice) | 西恩·威廉·斯科特
 | |
| (voice) | 昆瑙·内亚
 | |
| (voice) | 尼克·弗罗斯特
 | |
| (voice) | 艾伦·图代克
 | |
| Walter (voice) | 阿兹·安萨里
 | |
| Gossip Girl (voice) | 海瑟·莫里斯
 | |
| Raz | 瑞贝尔·威尔森
 | |
| (voice) | 詹妮特·麦柯迪
 | |
| (voice) | 乔什·盖德
 | |
| Ethan (voice) (as Drake) | Aubrey Graham
 | |
| Peaches (voice) | 柯柯·帕尔莫
 | |
| (voice) | 尼姬·米纳什
 | |
| Granny (voice) | 旺达·塞克丝
 | |
| (voice) | 乔伊·贝哈尔
 | |
| (voice) | 阿兰·夏巴
 | |
| Marshall (voice) | 本·格雷伯曼
 | |
| Sloth Siren (voice) | Ester Dean
 | |
| Captain Gutt (voice) | 彼特·丁拉基
 | |
| Crab (voice) | Jason Fricchione | |
| Additional Voices | 贾森·哈里斯
 | |
| Hyrax | Alexa Kahn | |
| Meghan (voice) | Ally Romano | |
| Various Characters (voice) | 塔拉·杰恩
 | |
| Elk (voice) | Matthew Simmons | |
| Creature Siren / Various (voice) | Christopher Campbell | |
| Beaver (voice) | George Jacobs | |
| Panicked Start (voice) | James Palumbo | |
| Buck (voice) | 西蒙·佩吉
 | |
| Uncle Fungus (voice) | Eddie 'Piolin' Sotelo | |
| Ariscratle (voice) | 帕特里克·斯图尔特
 | |
| Baby Bird (voice) | Meghan Thurmeier | |
| Additional Voices (voice) | Ashley Albert | |
