| 角色 | 饰演者 | 角色介绍 |
| Mr. Popper | 金·凯瑞 | |
| Amanda | 卡拉·古奇诺 | |
| Mrs. Van Gundy | 安吉拉·兰斯伯瑞 | |
| Pippi | 奥菲利亚·拉维邦德 | |
| Janie | 玛德琳·卡罗尔 | |
| Nat Jones | 克拉克·格雷格 | |
| Mr. Gremmins | 杰弗里·塔伯 | |
| Kent | 大卫·克鲁霍尔特兹 | |
| Franklin | 菲利浦·贝克·霍尔 | |
| Billy | Maxwell Perry Cotton | |
| Rick | 詹姆士·塔珀 | |
| Reader | Dominic Chianese | |
| Yates (as William C. Mitchell) | William Charles Mitchell | |
| Tommy's Mom | Kelli Barrett | |
| Young Tommy Popper #2 | Dylan Clark Marshall | |
| Young Tom Popper Sr (voice) | 布莱恩T·德莱尼 | |
| Gremmins's Secretary | Elaine Cusick | |
| Town Car Driver (as Harlin C. Kearsley) | Harlin Kearsley | |
| Daryl | Desmin Borges | |
| Reginald | Lee Moore | |
| Tito | Dominic Colon | |
| Freddy | Jeff Lima | |
| Klaus | Frank Ciornei | |
| Arnold | J.R. Horne | |
| Arctic Friend (voice) | Matthew Wolf | |
| Animal Control Guy | Andrew Stewart-Jones | |
| Fish & Game Officer | 詹姆斯·陈 | |
| Marine & Waterfowl Officer | Rafael Osorio | |
| Sanitation Officer | Curtis Shumaker | |
| Random Man on Street | Joe D'Onofrio | |
| Nanny | Olga Merediz | |
| Tavern Hostess | Betsy Aidem | |
| Fishmonger (as Angel L. Caban) | Angel Caban | |
| Young Developer | Chris Beetem | |
| Old Tom Popper Sr. (voice) | Charles L. Campbell |
