| Strider Hiryuu (voice) (as Tomomi Fube) | 鸟海浩辅
 | |
| Rockman / Roll (voice) | Kaoru Fujino | |
| Morrigan Aensland / 'Lilith' / Devilot (voice) | Yayoi Jinguji | |
| Chun-Li / Shadow Lady (voice) | 宫村优子
 | |
| Ryu / Shadow (voice) | 森川智之
 | |
| Captain Commando (voice) | 长嶝高士
 | |
| Zangief / Mech-Zangief (voice) | 高木涉
 | |
| The Incredible Hulk (voice) | 安德鲁·杰克逊
 | |
| Jin Saotome (voice) | 上田祐司
 | |
| Jubilee (voice) | Alyson Court | |
| Wolverine / Logan / Captain America / Steve Rogers / U.S. Agent / Jack Daniels (voice) | Cathal J. Dodd | |
| Onslaught (voice) (as Maurice Wint) | Maurice Dean Wint | |
| Spider-Man (voice) | Patrick Chilvers | |
| Venom / Thor (voice) | Rod Wilson | |
| Gambit (voice) | Tony Daniels | |
| War Machine (voice) | Wayne Ward | |
| Announcer (voice) | 莎莉·卡希尔 | |
| Juggernaut (voice) (uncredited) | Rick Bennett | |
| Psylocke / Elisabeth 'Betsy' Braddock / Storm / Ororo Munroe (voice) (uncredited) | Catherine Disher | |
| Colossus (voice) (uncredited) | Dan Hennessey | |
| Magneto (voice) (uncredited) | Lorne Kennedy | |
| Cyclops / Scott Summers (voice) (uncredited) | Norm Spencer | |
