| 角色 | 饰演者 | 角色介绍 |
| Lucy Eleanor Moderatz | 桑德拉·布洛克 | |
| Jack Callaghan | 比尔·普尔曼 | |
| Peter Callaghan | 彼得·盖勒 | |
| Elsie | 格莱妮丝·约翰斯 | |
| Joe 'Joey' Fusco Jr. | 迈克尔·瑞斯玻利 | |
| Ashley Bartlett Bacon | 艾利·沃克 | |
| Mary Callaghan | 莫尼卡·凯娜 | |
| Dr. Rubin | 迪克·库萨克 | |
| Midge Callaghan | Micole Mercurio | |
| Jerry Wallace | Jason Bernard | |
| Nurse Wanda | Ruth Rudnick | |
| Celeste | Marcia Wright | |
| Man in Peter's Room | Thomas Q. Morris | |
| Doorman | Bernie Landis | |
| Dalton Clarke | James Krag | |
| Orderly | Rick Worthy | |
| Intern | Marc Grapey | |
| Priest | Joel Hatch | |
| Joe Fusco Sr. | Mike Bacarella | |
| Hot Dog Vendor | Peter Siragusa | |
| Man in Church | Gene Janson | |
| Phyllis | Krista Lally | |
| Cop at ICU | Kevin Gudahl | |
| Blood Donor Nurse | Ann Whitney | |
| Admitting Nurse | Margaret Travolta | |
| Ashley's Husband | Shea Farrell | |
| Beth | Kate Reinder | |
| Celeste's Friend | Susan Messing | |
| Lucy's Father | Richard Pickren | |
| Young Lucy | Megan Schaiper | |
| Mailman | Dobie Maxwell | |
| Bit (uncredited) | Robert Minkoff | |
| Ox Callaghan | 彼得·伯耶尔 |
