| 角色 | 饰演者 | 角色介绍 |
| Aaron Hotchner? (185 episodes 2005-2013) | 托马斯·吉布森 | |
| Derek Morgan (185 episodes 2005-2013) | 谢默·摩尔 | |
| Dr. Spencer Reid (185 episodes 2005-2013) | 马修·格雷·古柏勒 | |
| Penelope Garcia (183 episodes 2005-2013) | 克里斯汀·范奈丝 | |
| Jennifer Jareau? (164 episodes 2005-2013) | A·J·库克 | |
| David Rossi (135 episodes 2007-2013) | 乔·曼特纳 | |
| Emily Prentiss (125 episodes 2006-2012) | 帕姬·布鲁斯特 | |
| Swat Leader (67 episodes 2005-2009) | John Barton | |
| Jason Gideon (47 episodes 2005-2007) | 曼迪·帕廷金 | |
| Elle Greenaway (28 episodes 2005-2006) | 劳拉·格劳蒂尼 | |
| Alex Blake (24 episodes 2012-2013) | 珍妮·特里普里霍恩 | |
| Erin Strauss (22 episodes 2007-2013) | Jayne Atkinson | |
| Kevin Lynch (19 episodes 2007-2013) | 尼古拉斯·布兰登 | |
| Jack Hotchner (17 episodes 2007-2013) | Cade Owens | |
| Ashley Seaver (13 episodes 2010-2011) | 瑞秋·尼科尔斯 | |
| Haley Hotchner (13 episodes 2005-2009) | 梅乐迪丝·梦露 | |
| Agent Anderson? (13 episodes 2005-2013) | Brian Appel | |
| Detective William LaMontagne Jr.? (10 episodes 2007-2013) | 乔什·斯图沃特 | |
| Jordan Todd? (8 episodes 2008-2009) | Meta Golding | |
| Beth Clemmons (8 episodes 2011-2013) | Bellamy Young |
