| 角色 | 饰演者 | 角色介绍 |
| James Ubriacco | 约翰·特拉沃塔 | |
| Mollie Ubriacco | 柯尔斯蒂·艾利 | |
| Rosie | 奥林匹亚·杜卡基斯 | |
| Albert | 乔治·席格 | |
| Grandpa | Abe Vigoda | |
| Mikey (voice) | 布鲁斯·威利斯 | |
| Rona | 吐温克·卡潘 | |
| Mikey | Jason Schaller | |
| Mikey | Jaryd Waterhouse | |
| Mikey | Jacob Haines | |
| Mikey | Christopher Aydon | |
| Melissa | Joy Boushel | |
| Dr. Fleisher | 唐·戴维斯 | |
| Lou | Louis Heckerling | |
| Secretary | Brenda Crichlow | |
| Salesgirl | Andrea Mann | |
| Cab Stealer | Douglas Tuck | |
| Street Worker | Alex Bruhanski | |
| Admitting Clerk | Casey Grant | |
| Hospital Worker | Oscar B. Ramos | |
| Orderly | Aurelio Dinunzio | |
| Admitting Doctor | Jeff Irvine | |
| Nurse | Shirley Barclay | |
| Drug Doctor | William B. Davis | |
| Mr. Impatience | David Berner | |
| Mr. Anal | Jerry Wasserman | |
| Carrie | Daliah Bache | |
| Lupe | Zena Darawalla | |
| Harry | Nicholas Rice | |
| Mr. Russ | 尼尔·伊斯雷尔 | |
| Director | 布鲁·曼库玛 | |
| Home Orderly | William Britos | |
| Burly Orderly | Dee Jay Jackson | |
| Lady | Isa Burner | |
| Lady | Bea Cartwell | |
| Lady | Eleanor Haines | |
| Little Girl | Mollie Israel | |
| Little Boy | Ryan McIntosh | |
| Pilot Friend | Gerry Bean | |
| Pilot Friend | Deryl Hayes | |
| Ester | Enid Saunders | |
| Silly Baby | Nicole Stevens | |
| Baby Megan | Christy Smith | |
| Sand Box Baby | Sabrina Bailey |
