| Lum (voice) | 平野文
 | |
| Ataru Moroboshi (voice) | 古川登志夫
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| Shutaro Mendou (voice) | 神谷明
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| Shinobu (voice) | 岛津冴子
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| Ten (voice) | 杉山佳寿子
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| Sakura (voice) | 鹫尾真知子
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| Onsen-Mark Sensei (voice) | 池水通洋
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| Megane (voice) | 千叶繁
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| Perm (voice) | 村山明
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| Chibi (voice) | 二又一成
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| Kakugari (voice) | 野村信次
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| Ry?nosuke (voice) | 田中真弓
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| Ry?nosuke's Father (voice) | 安西正弘
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| Ryooko (voice) | 小山茉美
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| Ataru's Father (voice) | 绪方贤一
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| Ataru's Mother (voice) | 佐久间夏生
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| Lum's Father (voice) | 泽律雄
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| Lum's Mother (voice) | 山田礼子
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| Rei (voice) | 玄田哲章
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| Ran (voice) | 小宫和枝
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| Benten (voice) | 三田友子
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| Ruu (voice) | 铃木一辉
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| Ruu the Magician (voice) | 岩田光央
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| Lahla (voice) | 岛本须美
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| Oshima the Raccoon (voice) | 菅谷政子
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| Old Woman (voice) | 京田尚子
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| Oyuki (voice) | 小原乃梨子
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| Cherry (voice) | 永井一郎
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| Onsen Mark (voice: English version) | Bradley Evans | |
| Obaba Oshima Lum's Mom (voice: English version) | Kristen Foster | |
| Ruu (voice: English version) | Justin Geer | |
| Rei (voice: English version) | Jeremy Griffin | |
| Perm (voice: English version) | Jonathon Guggenheim | |
| Megane (voice: English version) | Colin Hackman | |
| Ran Ryuunsuke (voice: English version) | Morgan Jarrett | |
