| Madea | 泰勒·派瑞
 | |
| Aunt Bam | Cassandra Davis | |
| Miss Shirley | Chandra Currelley-Young | |
| Joyce | Cheryl Pepsii Riley | |
| Monroe (as Palmer E. Williams Jr) | Palmer Williams Jr. | |
| Tammy (as Chrissy Collins) | Crystal Collins | |
| Kimberly | Tamar Davis | |
| Byron | Jeffrey Lewis | |
| Donnie | Zuri Craig | |
| Karen | Brandi Milton | |
| Rose | Chontelle Moore | |
| Harold | Danny Clay | |
| Jason | Rico Ball | |
| Dr. Wallace | Omarr Dixon | |
| Dr. Evans | Philip Anthony Rodriguez | |
| Patient | Michael L. Covington | |
| Tammy (as Natalie Desselle Reid) | 娜塔莉·狄赛尔
 | |
| Home Buyer | Rob Epstein | |
| Hospital Administrator | Shannon Guess | |
| Dr. Wallace | Quan Hodges | |
| Hospital visitor | Deborah Hurm | |
| The Nanny | Cindy Jefferson | |
| Kimberly | 香侬·凯恩
 | |
| Renee | 劳伦·伦敦
 | |
| Will | Nicholas Milton | |
| Maintenance Man | M.V. Oliphant | |
