| Jimmy Neutron (voice) | 德比·戴瑞巴里
 | |
| Timmy Turner (voice) | Tara Strong | |
| Carl/Anti-Fairy (voice) | Rob Paulsen | |
| Sheen/Anti-Fairy (voice) | Jeffrey Garcia | |
| Cindy Vortex (voice) | Carolyn Lawrence | |
| Libby (voice) | Crystal Scales | |
| Goddard/Special Vocal Effects (voice) | 弗兰克·维尔克
 | |
| Wanda/Mrs. Turner/Anti-Wanda (voice) | Susan Blakeslee | |
| Cosmo/Mr. Turner/Jorgen Von Strangle/Anti-Cosmo (voice) | Daran Norris | |
| Mr. Crocker (voice) | 卡洛斯·阿拉兹拉奎
 | |
| Binky (voice) (as Dee Baker) | Dee Bradley Baker | |
| A.J. (voice) (as Gary LeRoi Gray II) | Gary LeRoi Gray | |
| Chet Ubetcha (voice) | Jim Ward | |
| Dr. Moist (voice) | Jeff Bennett | |
| Morgan Freeman/Anti-Fairy (voice) | Kevin Michael Richardson
 | |
| Professor Finbarr Calamitous (voice) | 蒂姆·克里
 | |
| Francais (voice) | Faith S. Abrahams | |
| Judy Neutron (voice) | Megan Cavanagh | |
| Hugh Neutron (voice) | Mark DeCarlo | |
| Vicky (voice) | Grey DeLisle
 | |
| Chip Skylark (archive recording) (voice) | Chris Kirkpatrick | |
