| Sidney Prescott | 内芙·坎贝尔
 | |
| Dewey Riley | 大卫·阿奎特
 | |
| Gale Weathers-Riley | 柯特妮·考克斯
 | |
| Sherrie | 露西·海尔
 | |
| The Voice (voice) | 罗杰·L·杰克逊 | |
| Trudie | 施蕾·葛莱姆斯
 | |
| Ghostface | Dane Farwell | |
| Rachel | 安娜·帕奎因
 | |
| Chloe | 克里斯汀·贝尔
 | |
| Jenny Randall | 艾米·缇加登
 | |
| Marnie Cooper | 布丽特妮·罗伯森
 | |
| Rebecca Walters | 爱丽森·布里
 | |
| Kirby Reed | 海顿·潘妮蒂尔
 | |
| Jill Roberts | 艾玛·罗伯茨
 | |
| Olivia Morris | Marielle Jaffe | |
| Deputy Judy Hicks | 玛丽·谢尔顿
 | |
| TV Host | 南希·奥戴尔
 | |
| Robbie Mercer | 埃里克·克诺德森
 | |
| Film Geek (as Justin Brandt) | Justin Michael Brandt | |
| Charlie Walker | 罗瑞·卡尔金
 | |
| Trevor Sheldon | 尼可·托托雷拉
 | |
| Deputy Perkins | 安东尼·安德森
 | |
| Detective Hoss | 亚当·布罗迪
 | |
| Deputy Jenkins | Gordon Michaels | |
| Mr. Baker | John Lepard | |
| Reporter #2 | Kim Adams | |
| Reporter #3 | Devin Scillian | |
| Kate Roberts | 玛丽·麦克唐纳
 | |
| Dr. Orth | Mark Aaron Buerkle | |
| Reporter #1 | Julia Ho | |
| Cocky Student | Alex Punch | |
| Casey | 海瑟·格拉汉姆
 | |
| Reporter #4 | Glenda Lewis | |
| Reporter #5 | William Spencer | |
| Reporter #6 | Tim Doty | |
| Reporter #7 | Peter Carey | |
| Nerdy AV Student (uncredited) | Andrew Freij | |
| High School Student (uncredited) | Jairus Devon Hill | |
