| 角色 | 饰演者 | 角色介绍 |
| John Crowley | 布兰登·费舍 | |
| Dr. Robert Stonehill | 哈里森·福特 | |
| Aileen Crowley | 凯丽·拉塞尔 | |
| Megan Crowley | Meredith Droeger | |
| Patrick Crowley | Diego Velazquez | |
| John Crowley Jr. | Sam M. Hall | |
| Dr. Kent Webber | 杰瑞德·哈里斯 | |
| CEO Erich Loring | 帕特里克·波查 | |
| Pete Sutphen | 阿兰·卢克 | |
| Dr. Renzler | David Clennon | |
| Sal | 迪·沃伦斯-斯通 | |
| Marcus Temple | 考特尼·万斯 | |
| Wendy Temple | Ayanna Berkshire | |
| Dr. Preston | P.J. Byrne | |
| Dr. Allegria | Andrea White | |
| Niles | G.J. Echternkamp | |
| Vinh Tran | Vu Pham | |
| Cal Dunning | Derek Webster | |
| Renzler Scientist #1 | Jana Lee Hamblin | |
| Senior Scientist | Shelly Lipkin | |
| Researcher (as Chris Harder) | Christopher D. Harder | |
| Security Officer | Eric Derovanessian | |
| Reception Nurse | Patricia Ferguson | |
| Day Nurse (Jane) | Jeanette McMahon | |
| Julia | Brennan Claire | |
| Night Nurse (Marcy) | Tra'Renee Chambers | |
| Maria | Quigley Provost-Landrum | |
| ICU Nurse | Kimberly Howard | |
| Dr. Waldman | Lily Mariye | |
| Day Nurse (Kate) | Sherilyn Lawson | |
| ICU Doctor | Eric Martin Reid | |
| Stonehill?s Secretary | Sharonlee McLean | |
| Van Driver | Bryce Flint-Sommerville | |
| Nell Madden | Jeanine Jackson | |
| Webber's Assistant | Gavin Bristol |
