| Marco Polo | 加里·库柏
 | |
| Princess Kukachin | 茜瑞·格丽
 | |
| Ahmed | 巴兹尔·雷斯伯恩
 | |
| Binguccio | Ernest Truex | |
| Kaidu | 艾伦·海尔
 | |
| Kublai Khan | George Barbier | |
| Nazama | 宾妮·巴尼斯
 | |
| Nazama's Maid | 拉娜·特纳
 | |
| Bayan | Stanley Fields | |
| Toctai | Harold Huber | |
| Chen Tsu | HB·沃纳
 | |
| Chen Tsu's Son | Eugene Hoo | |
| Chen Tsu's Daughter | Helen Quan | |
| Chen Tsu's Wife (as Soo Young) | Soo Yong | |
| Chen Tsu's Mother | Mrs. Ng | |
| Visahka | Lotus Liu | |
| Persian Ambassador | Ferdinand Gottschalk | |
| Nicolo Polo | Henry Kolker | |
| Maffeo Polo | Hale Hamilton | |
| Chamberlain | Robert Greig | |
| Venetian Business Man (as Reginald Barlowe) | Reginald Barlow | |
| Venetian Business Man | Theodore von Eltz | |
| Kaidu Entertainer | Diane Toy | |
| Kaidu Guard | Harry Kerus | |
| Kaidu Maid | 格瑞塔·格兰斯泰德
 | |
| Kaidu Officer | Harry Cording | |
| Kaidu Officer | Dick Rich | |
| Kaidu Officer | Joe Woody | |
| Kaidu Officer | Leo Fielding | |
| Ahmed's Aide (uncredited) | Richard Alexander | |
| Venetian Business Man (uncredited) | Granville Bates
 | |
| Mongol Guard (uncredited) | 沃德·邦德
 | |
| (uncredited) | 理查德·法恩斯沃斯
 | |
| Court Girl (uncredited) | Mia Ichloka | |
| Tartar Warrior (uncredited) | James B. Leong | |
