| Col. Cord McNally | 约翰·韦恩
 | |
| Capt. Pierre Cordona aka Frenchy | Jorge Rivero | |
| Shasta Delaney | 詹妮弗·欧内尔
 | |
| Phillips | 杰克·伊莱姆
 | |
| Sgt. Tuscarora Phillips | Christopher Mitchum | |
| Ketcham (boss of Rio Lobo) | Victor French | |
| Maria Carmen (Tuscarora's girlfriend) | Susana Dosamantes
 | |
| Amelita | 雪莉·兰辛
 | |
| Dr. Ivor Jones (Rio Lobo dentist) | 大卫·哈斗斯顿
 | |
| Rio Lobo Sheriff 'Blue Tom' Hendricks | Mike Henry | |
| Blackthorne Sheriff Pat Cronin | 比尔·威廉姆斯
 | |
| Rio Lobo Deputy | 吉姆·戴维斯
 | |
| L/Cpl. Bide | Dean Smith | |
| Whitey Carter (Rio Lobo deputy) | Robert Donner
 | |
| Gunman #4 | George Plimpton | |
| Lt. Harris | Edward Faulkner | |
| Lt. Forsythe (gold train detail officer) | Peter Jason
 | |
| Chuck | Chuck Courtney | |
| Gunman #3 | Robert Rothwell | |
| Feeny (bartender of saloon outside POW camp) (uncredited) | 唐·瑞德·巴里
 | |
| (uncredited) | Harold Cops | |
| (uncredited) | Stanley Corson | |
| (uncredited) | 桑德拉·库瑞
 | |
| (uncredited) | José Espinosa | |
| (uncredited) | Chuck Hayward | |
| Picket (uncredited) | Lance Hool | |
| (uncredited) | Frank Kennedy | |
| (uncredited) | Charlie Longfoot | |
| (uncredited) | John McKee | |
| Train engineer (uncredited) | Boyd 'Red' Morgan | |
