| Ash Ketchum/Mrs. Delia Ketchum (voice) | Veronica Taylor | |
| Misty/Jesse (voice) | Rachael Lillis | |
| Brock/James (voice) | Eric Stuart | |
| Meowth (voice) (as Maddie Blaustein) | Madeleine Blaustein | |
| Pikachu (voice) | 大谷育江
 | |
| Molly Hale (voice) | Amy Birnbaum | |
| Spencer Hale/Entei (voice) | Dan Green | |
| Prof. Samuel Oak (voice) | Stan Hart | |
| (voice) | Lisa Ortiz | |
| (voice) | Kathy Pilon | |
| (voice) | Peter R. Bird | |
| (voice) | Kayzie Rogers | |
| Skyler (voice) (as Ed Paul) | Ed Paul | |
| (voice) | Ken Gates | |
| (voice) | 塔拉·杰恩
 | |
| (voice) | Lee Quick | |
| (voice) | Roger Kay | |
| Narrator (voice) | Phillip Bartlett | |
| Meowth (voice) | Tommy Karlsen | |
| Tracy (voice: English version) (as Ed Paul) | Ted Lewis | |
| Onix (voice) | 石塚运升
 | |
| Togepi (voice) | 兴梠里美 | |
