| Sydney Bristow (105?episodes 2001-2006) | 珍妮弗·加纳
 | |
| Arvin Sloane (105?episodes 2001-2006) | 朗·瑞弗金
 | |
| Michael Vaughn (95?episodes 2001-2006) | 迈克尔·瓦尔坦
 | |
| Will Tippin (46?episodes 2001-2006) | 布莱德利·库珀
 | |
| Lauren Reed (23?episodes 2003-2005) | 梅丽莎·乔治
 | |
| Nadia Santos (31?episodes 2004-2006) | 米亚·梅塞德罗
 | |
| Renée Rienne (11?episodes 2005-2006) | 艾洛迪·布歇
 | |
| Thomas Grace (17?episodes 2005-2006) | 巴萨扎·盖提
 | |
| Irina Derevko (27?episodes 2002-2006) | 莉娜·奥琳
 | |
| Francie Calfo?/ ... (48?episodes 2001-2006) | Merrin Dungey | |
| Marcus Dixon (105?episodes 2001-2006) | 卡尔·鲁伯利
 | |
| Marshall Flinkman (105?episodes 2001-2006) | 凯文·韦斯曼
 | |
| Eric Weiss (68?episodes 2001-2006) | 格雷戈·格伦伯格
 | |
| Julian Sark?/ ... (56?episodes 2002-2006) | 大卫·安德斯
 | |
| Rachel Gibson (17?episodes 2005-2006) | 瑞秋·尼科尔斯
 | |
| Jack Bristow (105?episodes 2001-2006) | 维克托·加柏
 | |
| F.B.I. Asst. Director Kendall (18?episodes 2002-2004) | 特瑞·欧奎恩
 | |
| Kelly Peyton (13?episodes 2005-2006) | 艾米·阿克
 | |
| Dr. Judy Barnett (12?episodes 2002-2004) | 帕特丽夏·温迪
 | |
| Arthur Devlin (9?episodes 2001-2006) | James Handy | |
| Emily Sloane (9?episodes 2002-2005) | 艾米·欧文 | |
