| 角色 | 饰演者 | 角色介绍 |
| Margaret Thatcher | 梅丽尔·斯特里普 | |
| Denis Thatcher | 吉姆·布劳德本特 | |
| Carol Thatcher | 奥莉薇娅·柯尔曼 | |
| June | 苏珊·布朗 | |
| Cleaner | Alice da Cunha | |
| Susie | Phoebe Waller-Bridge | |
| Alfred Roberts | 伊恩·格雷 | |
| Young Margaret Thatcher | 亚历珊德拉·罗奇 | |
| Muriel Roberts | Victoria Bewick | |
| Beatrice Roberts | Emma Dewhurst | |
| Young Denis Thatcher | 哈里·劳埃德 | |
| Hostess 1949 | 斯薇斯特·L·唐兹尔 | |
| Host 1949 | Michael Culkin | |
| Female Guest 1949 | Stephanie Jacob | |
| Grey Suited Guest 1949 | 罗伯特·波特尔 | |
| Male Guest 1949 | 理查德·迪克逊 | |
| Amanda | 阿曼达·鲁特 | |
| James R | Clifford Rose | |
| William | Michael Cochrane | |
| James T | Jeremy Clyde | |
| Peter | Michael Simkins | |
| Young Carol | Eloise Webb | |
| Young Mark | Alexander Beardsley | |
| Airey Neave | Nicholas Farrell | |
| Edward Heath | 约翰·塞森斯 | |
| Geoffrey Howe | 安东尼·海德 | |
| House of Commons Speaker | Richard Syms | |
| Reg Prentice | 大卫·维斯特海德 | |
| Francis Pym | Julian Wadham | |
| Michael Heseltine | 理查德·格兰特 | |
| John Nott | Angus Wright | |
| Gordon Reece | 罗杰·阿拉姆 | |
| Michael Foot | 迈克尔·潘宁顿 | |
| Cabinet Minister | John Harding | |
| Cabinet Minister | Simon Chandler | |
| Cabinet Minister | Stephen Boxer | |
| Cabinet Minister | Jasper Jacob | |
| Cabinet Minister | Rupert Vansittart |
