| Nemo Nobody adult / Nemo Nobody aged 118 | 杰瑞德·莱托
 | |
| Elise | 萨拉·波莉
 | |
| Anna / Anna #2 | 黛安·克鲁格
 | |
| Nemo's Father | 瑞斯·伊凡斯
 | |
| Nemo age 16 | 托比·瑞格波
 | |
| Young journalist | 丹尼尔·梅斯
 | |
| Anna age 15 | 朱诺·坦普尔
 | |
| Elise age 15 | 克莱尔·斯通
 | |
| Beggar in the railway station | 切瑞拉·凯瑟莉
 | |
| Jean (as Linh-Dan Pham) | 范林丹
 | |
| Peter | Daniel Brochu | |
| Nemo age 9 | Thomas Byrne | |
| Anna's daughter | Katharina Pejcic | |
| Black man at airport | Nicholas Beveney | |
| Thug 1 | David Schaal
 | |
| (uncredited) | Jan Hammenecker | |
| Anna's school friend | Tanya Trombetta | |
| Hotel entrance guard | Pierre Chaves | |
| Police officer | 卡洛·麦斯罗尼
 | |
| Man in black 1 | 洛朗·卡佩路
 | |
| Noah | Anders Morris | |
| Nemo age 5 | Noa De Costanzo | |
| Coma nurse 1 | Christelle Cornil | |
| Shoelace dealer | Serge Larivière | |
| Eve | Emily Tilson | |
| TV host | Harold P. Manning | |
| Continuity girl | Virginie Bordes | |
| Anna's son | Alexander Türk | |
| (uncredited) | Sandrine Laroche | |
| (uncredited) | Didier De Neck | |
| Young girl (uncredited) | Thamea Winterfeld | |
| Daughter at Station | Valentina Dolla | |
| Stefano | Ben Mansfield | |
| Nemo's Mother | Natasha Little | |
| Julian | 瓦伦汀·达恩恩斯
 | |
| Bubble Boy | Joel Cross | |
| Anna & Nemo's son | Aaron Landt | |
