| 角色 | 饰演者 | 角色介绍 |
| Ethan Hunt | 汤姆·克鲁斯 | |
| Sean Ambrose | 多格雷·斯科特 | |
| Nyah Nordoff-Hall | 桑迪·牛顿 | |
| Luther Stickell | 文·瑞姆斯 | |
| Hugh Stamp | 理查德·劳斯伯格 | |
| Billy Baird | 约翰·波尔森 | |
| John C. McCloy | 布莱丹·格里森 | |
| Dr. Nekhorvich (as Radé Sherbedgia) | 拉德·舍博德兹加 | |
| Wallis | 威廉·麦鲍瑟 | |
| Ulrich | 多米尼克·珀塞尔 | |
| Michael | Matthew Wilkinson | |
| Accountant | Nicholas Bell | |
| Flamenco Dancer | Cristina Brogers | |
| Chemist | Kee Chan | |
| Larrabee | Kim Fleming | |
| Biocyte Security Guard #2 | Alan Lovell | |
| Relief Pilot | Dan Luxton | |
| Dr. Gradsky | Christian Manon | |
| Biocyte Security Guard #1 | 卡尔·麦克米兰 | |
| Bookie | Lester Morris | |
| Flamenco Dancer | Kelly Ons | |
| Prison Guard #2 | Nicholas Papademetriou | |
| Biocyte Security Guard #3 | Brett Partridge | |
| Flamenco Dancer | Candice Partridge | |
| Flamenco Dancer | Natalie Reis | |
| Co-Pilot | Daniel Roberts | |
| Flamenco Dancer | Adriana Rodríguez | |
| Flamenco Dancer | Sandra Rodríguez | |
| Flamenco Dancer | Nada Rogic | |
| Senor De L'Arena | Antonio Vargas | |
| Actor (uncredited) | Alison Araya | |
| Gate Guard #1 (uncredited) | Mark Connolly | |
| Mission Commander Swanbeck (uncredited) | 安东尼·霍普金斯 | |
| Train Driver (uncredited) | 帕特里克·马博 |
