| Ethan Hunt | 汤姆·克鲁斯
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| Sean Ambrose | 多格雷·斯科特
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| Nyah Nordoff-Hall | 桑迪·牛顿
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| Luther Stickell | 文·瑞姆斯
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| Hugh Stamp | 理查德·劳斯伯格
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| Billy Baird | 约翰·波尔森
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| John C. McCloy | 布莱丹·格里森
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| Dr. Nekhorvich (as Radé Sherbedgia) | 拉德·舍博德兹加
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| Wallis | 威廉·麦鲍瑟
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| Ulrich | 多米尼克·珀塞尔
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| Michael | Matthew Wilkinson | |
| Accountant | Nicholas Bell | |
| Flamenco Dancer | Cristina Brogers | |
| Chemist | Kee Chan | |
| Larrabee | Kim Fleming | |
| Biocyte Security Guard #2 | Alan Lovell | |
| Relief Pilot | Dan Luxton | |
| Dr. Gradsky | Christian Manon | |
| Biocyte Security Guard #1 | 卡尔·麦克米兰
 | |
| Bookie | Lester Morris | |
| Flamenco Dancer | Kelly Ons | |
| Prison Guard #2 | Nicholas Papademetriou | |
| Biocyte Security Guard #3 | Brett Partridge | |
| Flamenco Dancer | Candice Partridge | |
| Flamenco Dancer | Natalie Reis | |
| Co-Pilot | Daniel Roberts | |
| Flamenco Dancer | Adriana Rodríguez | |
| Flamenco Dancer | Sandra Rodríguez | |
| Flamenco Dancer | Nada Rogic | |
| Senor De L'Arena | Antonio Vargas | |
| Actor (uncredited) | Alison Araya | |
| Gate Guard #1 (uncredited) | Mark Connolly | |
| Mission Commander Swanbeck (uncredited) | 安东尼·霍普金斯
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| Train Driver (uncredited) | 帕特里克·马博 | |
